Ill. woman killed same day sister sat behind Obama

In this photo taken Friday, Feb. 15, 2013, in Chicago, President Barack Obama speaks about the nations struggle with gun violence at an appearance at Hyde Park Academy. An 18-year-old Chicago woman was killed the same day, hours after her sister had sat on the stage behind President Obama, listening to him push for gun control legislation. Janay Mcfarlane was shot once in the head around 11:30 p.m. Friday in North Chicago, Lake County Coroner Thomas Rudd told the Chicago Sun-Times. McFarlane's sister 14 year-old Destini, attended Obama's speech. (AP Photo/M. Spencer Green)

In this photo taken Friday, Feb. 15, 2013, in Chicago, President Barack Obama speaks about the nations struggle with gun violence at an appearance at Hyde Park Academy. An 18-year-old Chicago woman was killed the same day, hours after her sister had sat on the stage behind President Obama, listening to him push for gun control legislation. Janay Mcfarlane was shot once in the head around 11:30 p.m. Friday in North Chicago, Lake County Coroner Thomas Rudd told the Chicago Sun-Times. McFarlane's sister 14 year-old Destini, attended Obama's speech. (AP Photo/M. Spencer Green)

CHICAGO (AP) ? An 18-year-old Chicago woman was killed the same day her sister had sat on the stage behind President Barack Obama, listening to him push for gun control legislation.

Janay Mcfarlane was shot once in the head around 11:30 p.m. Friday in North Chicago, Lake County Coroner Thomas Rudd told the Chicago Sun-Times (http://bit.ly/12Uoh9b). Mcfarlane, a mother of a 3-month-old boy, was in the Chicago suburb visiting friends and family.

North Chicago police said two people are being questioned in connection with Mcfarlane's death, but no charges have been filed.

"I really feel like somebody cut a part of my heart out," Angela Blakely, Mcfarlane's mother, said.

Blakely said the bullet that killed Mcfarlane was meant for a friend.

Hours earlier, Mcfarlane's 14-year-old sister was feet from Obama at Hyde Park Career Academy, where he spoke about gun violence and paid tribute to Hadiya Pendleton, the 15-year-old honor student fatally shot last month in a South Side park. Police have said it was a case of mistaken identity, and two people have been charged.

Pendleton's death was one of more than 40 homicides in Chicago in January, a total that made it the deadliest January in the city in more than a decade. Pendleton, a drum majorette, had recently performed during Obama's inauguration and the slaying happened about a mile from his Chicago home.

Blakely told the newspaper that Janay Mcfarlane had been affected by Pendleton's death.

"She always said after Hadiya Pendleton got killed, 'Momma that's so sad,'" Blakely said. "She was always touched by any kid that got killed. She was always touched by mothers who couldn't be there for their babies because they were gone."

Mcfarlane was supposed to graduate from an alternative school this spring, Blakely said, and wanted to go into the culinary arts.

"I'm just really, truly just trying to process it ? knowing that I'm not taking my baby home anymore," Blakely said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-02-17-US-Chicago-Violence/id-1101f02896204ec89adc4dfe2a8de288

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Katy Perry Ring NOT Sign of Engagement to John Mayer, Thank Goodness

Source: http://www.thehollywoodgossip.com/2013/02/katy-perry-not-engaged-to-john-mayer-thank-goodness/

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Barry Greenstein Allegedly Uncovers Security Error In Chinese Poker App

One of the biggest ?new? disciplines of poker that have come out in the recent past is that of Chinese Poker. Furthermore, its direct descendant, Open Face Chinese Poker, seems to have captured the fancy of high stakes poker professionals around the world. Yesterday, however, one of those poker pros allegedly uncovered an error in an application that would allow someone to cheat at the game.

Poker Hall of Fame member, three time World Series of Poker bracelet winner and two-time World Poker Tour champion (OK, he has some credentials) Barry Greenstein penned a blog yesterday for PokerStars that pointed out this flaw in an application (or ?app?) that is available for the iPhone and the iPad. ?I just started to play the game?I?m not real good as (of) yet,? Greenstein reported and, when he heard about the app for the Apple products, he decided to download the game for himself to attempt to improve his skills.

Playing against other unnamed poker professionals, Greenstein detailed out how he moved up from playing for $10 a point (and getting beat at the beginning) to playing for $25 a point. Greenstein would end up playing against another professional for $50 a point. Greenstein writes, ?I?d heard he might be a better player than I was, (but) I though perhaps I could learn playing against a better player.? Greenstein would go on to hammer the unnamed pro for 100 points (doing the math, that?s $5000).

The losing pro decided to try again, doubling the stakes against Greenstein, which he accepted. This is where the story begins to get a bit strange, according to Greenstein?s report.

?That?s when he started winning,? Barry reported. ?It?s not that he beat me, but it is how he beat me. He kept getting saved on the river over and over and over?when he had to get an out on the river to beat me, I wanted to see what his percentage was. The next 14 times it came up, he hit seven times. It was enough that after that I quit.?

Greenstein went to one of his nephews, a computer programmer, and asked him to take a look at the app to see if a player could change the cards. Within 30 minutes, Greenstein?s nephew reported back that anyone who was a programmer ? or knew a programmer ? who could hook an iPad into a computer could easily cheat. Greenstein asked for a demonstration and his nephew complied, showing him how easy it was to manipulate the program to not only change your cards but also to see what your opponent was holding.

Greenstein used the experience to warn his readers. ?You have to be very wary when playing for any significant sum of money on some of these games that may come out in the future. Secondly, as a general gambling premise, if you go somewhere and you lose and you don?t understand why you?re losing ? especially if you seem to be losing in ways that don?t seem right to you ? you have to quit. If there?s one game where you think the players are better than you but you do okay, go and play in that one even if there might be another game where the players seem really bad, but you don?t win.?

Greenstein isn?t blaming the publisher of the game for the issues that arose. ?When the programmers wrote this Open Face Chinese Poker app, they didn?t know people were going to be playing for lots of money using it. So they didn?t write it in a secure way because they thought it was just a fun game people would play for free. It?s not even really their fault.?

Apparently Greenstein?s experience with the game has brought some action from the publisher. According to PokerNews, a Tweet from @ChineseOpenFace regarding the app errors explained, ?The current update that is waiting for review in the App Store addresses the security issue Barry Greenstein mentions in his latest blog.? As those reviews can be a time consuming process, it isn?t known when it will be updated to the game.

Want the latest poker news in your twitter feed? Follow PokerNewsDaily on Twitter.

Source: http://www.pokernewsdaily.com/barry-greenstein-allegedly-uncovers-security-error-in-chinese-poker-app-23291/

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An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer

Abstract: In the absence of HER2 overexpression, triple-negative breast cancers (TNBCs) rely on signaling by epidermal growth factor receptor (EGFR/ErbB1/HER1) to convey growth signals and stimulate cell proliferation. Soluble EGF-like ligands are derived from their transmembrane precursors by ADAM proteases, but the identity of the ADAM that is primarily responsible for ligand release and activation of EGFR in TNBCs is not clear. Using publicly available gene expression data for patients with lymph node-negative breast tumors who did not receive systemic treatment, we show that ADAM12L is the only ADAM with an expression level significantly associated with decreased distant metastasis-free survival times. Similar effect was not observed for patients with ER-negative non-TNBCs. There was a positive correlation between ADAM12L and HB-EGF and EGFR in TNBCs, but not in ER-negative non-TNBCs. We further demonstrate that ectopic expression of ADAM12L increased EGFR phosphorylation in a mouse intraductal xenograft model of early breast cancer. Finally, we detect strong correlation between the level of anti-ADAM12L and anti-phospho-EGFR immunostaining in human breast tumors using tissue microarrays. These studies suggest that ADAM12L is the primary protease responsible for the activation of EGFR in early stage, lymph node-negative TNBCs. Thus, our results may provide novel insight into the biology of TNBC.

Source: http://experts.kumc.edu/works/35464

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Baseball: FSU beats Rhode Island in opener

Published: Saturday, February 16, 2013 at 14:07 PM.

FSU 11, Rhode Island 5

TALLAHASSEE ? Jose Brizuela belted a grand-slam home run in the sixth inning as Florida State took advantage of six walks and five hit batters in a season-opening win.

Marcus Davis added a two-run homer in the first inning and Justin Gonzalez drove in two runs for the Seminoles. Brandon Leibrandt was the winning pitcher despite allowing four earned runs in five innings.

Mike Lebel had a homer and single and three RBIs for Rhode Island.

Source: http://www.newsherald.com/sports/fsu/baseball-fsu-beats-rhode-island-in-opener-1.96715

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